Recent Publications

The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses 
Martinez DR et al., Sci Transl Med. 2024 May 22;16(748):eadj4504. doi: 10.1126/scitranslmed.adj4504. Epub 2024 May 22. PMID: 38776389.

Vaccine-mediated protection against Merbecovirus and Sarbecovirus challenge in mice
Martinez DR et al., Cell Rep. 2023 Oct 31;42(10):113248. doi: 10.1016/j.celrep.2023.113248. Epub 2023 Oct 18. PMID: 37858337; PMCID: PMC10842144.

A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice
Martinez DR et al., Sci Transl Med. 2022 Jan 26;14(629):eabj7125. doi: 10.1126/scitranslmed.abj7125. Epub 2022 Jan 26. PMID: 34726473; PMCID: PMC8899823.

Dengue Vaccines: The Promise and Pitfalls of Antibody-Mediated Protection
Martinez DR et al., Cell Host Microbe. 2021 Jan 13;29(1):13-22. doi: 10.1016/j.chom.2020.12.011. PMID: 33444553.

Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice
Martinez DR et al., Science. 2021 Aug 27;373(6558):991-998. doi: 10.1126/science.abi4506. Epub 2021 Jun 22. PMID: 34214046; PMCID: PMC8899822.

Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice
Martinez DR et al., Cell Rep. 2021 Jul 27;36(4):109450. doi: 10.1016/j.celrep.2021.109450. Epub 2021 Jul 10. PMID: 34289384; PMCID: PMC8270748.

Antigenic Variation of the Dengue Virus 2 Genotypes Impacts the Neutralization Activity of Human Antibodies in Vaccinees
Martinez DR et al., Cell Rep. 2020 Oct 6;33(1):108226. doi: 10.1016/j.celrep.2020.108226. PMID: 33027653; PMCID: PMC7583086.

Maternal Broadly Neutralizing Antibodies Can Select for Neutralization-Resistant, Infant-Transmitted/Founder HIV Variants
Martinez DR et al., mBio. 2020 Mar 10;11(2):e00176-20. doi: 10.1128/mBio.00176-20. PMID: 32156815; PMCID: PMC7064758.

Fc Characteristics Mediate Selective Placental Transfer of IgG in HIV-Infected Women
Martinez DR et al., Cell. 2019 Jun 27;178(1):190-201.e11. doi: 10.1016/j.cell.2019.05.046. Epub 2019 Jun 13. PMID: 31204101; PMCID: PMC6727200.

Maternal Binding and Neutralizing IgG Responses Targeting the C-Terminal Region of the V3 Loop Are Predictive of Reduced Peripartum HIV-1 Transmission Risk. Martinez DR et al., J Virol. 2017 Apr 13;91(9):e02422-16. doi: 10.1128/JVI.02422-16. PMID: 28202762; PMCID: PMC5391478.